Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647415 | 0.89 | HIF1A (0.47) | SMN1; SMN2ALDH1A1KMT2AHIF1AMAPT | |
| SCHEMBL4645027 | 0.84 | MMP1 (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4648540 | 0.83 | MMP1 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4645874 | 0.82 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL4644760 | 0.81 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL4647116 | 0.81 | MMP1 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4646053 | 0.81 | MMP1 (0.71) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4646819 | 0.81 | MAPT (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4646849 | 0.80 | MMP1 (0.68) | SMN1; SMN2ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL15708527 | 0.80 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |