Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.64 |
| ▸ | MMP2 | P08253 | 5/20 | 0.64 |
| ▸ | MMP9 | P14780 | 5/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646053 | 0.86 | MMP1 (0.71) | MMP1MMP2MMP9MAPK1HIF1A | |
| SCHEMBL4645874 | 0.85 | ALDH1A1 (0.57) | MMP1MMP2MMP9MAOBMAOA | |
| SCHEMBL4646853 | 0.84 | MGLL (0.55) | MMP1MMP2MMP9HIF1AALDH1A1 | |
| SCHEMBL4645027 | 0.84 | MMP1 (0.61) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL4647915 | 0.83 | SMN1; SMN2 (0.56) | MMP1MMP2MMP9HIF1AALDH1A1 | |
| SCHEMBL4647415 | 0.83 | HIF1A (0.47) | MMP1MMP2MMP9MAOBMAOA | |
| SCHEMBL4648115 | 0.83 | HIF1A (0.51) | MMP1MMP2MMP9MAOBMAOA | |
| SCHEMBL15708843 | 0.82 | MMP1 (0.73) | MMP1MMP2MMP9MAOBMAOA | |
| SCHEMBL15708841 | 0.82 | MMP1 (0.73) | MMP1MMP2MMP9MAOBMAOA | |
| SCHEMBL15708460 | 0.82 | MMP1 (0.73) | MMP1MMP2MMP9MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |