SCHEMBL4648009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7607159	0.88	ALDH1A1 (0.64)	ALDH1A1TSHRTP53CYP3A4THRB
	SCHEMBL4642537	0.87	ALDH1A1 (0.59)	ALDH1A1TSHRTP53CYP3A4THRB
	SCHEMBL596349	0.87	ALDH1A1 (0.62)	ALDH1A1TSHRTP53CYP3A4THRB
	SCHEMBL4648012	0.84	ALDH1A1 (0.43)	ALDH1A1TP53CYP3A4PRKCA
	SCHEMBL4866874	0.84	ALDH1A1 (0.66)	ALDH1A1TSHRTP53CYP3A4THRB
	Methacrylic Acid SCHEMBL19280555	0.83	ALDH1A1 (0.45)	ALDH1A1TSHR
	Methacrylic Acid SCHEMBL5690251	0.83	ALDH1A1 (0.45)	ALDH1A1TSHR
	SCHEMBL7517250	0.81	ALDH1A1 (0.71)	ALDH1A1TSHRTP53CYP3A4THRB
	SCHEMBL4644701	0.80	ALDH1A1 (0.60)	ALDH1A1TSHRTP53CYP3A4THRB
	SCHEMBL9859543	0.80	ALDH1A1 (0.60)	ALDH1A1TSHRTP53CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.