Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596349 | 0.90 | ALDH1A1 (0.62) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL18889150 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL2789568 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL4644701 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL4866878 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL4648009 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53CYP3A4THRB | |
| SCHEMBL7607159 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL35507 | 0.80 | TSHR (0.63) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL27827895 | 0.79 | ALDH1A1 (0.89) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL18071037 | 0.78 | CA2 (0.43) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006623-A | Good mechanical, electrical characteristics | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | claimed |