SCHEMBL4648203

SCHEMBL4648203

FC(F)(F)C(F)(F)C(F)(F)OBr

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747340 0.71
SCHEMBL867248 0.69 LMNA (0.32) LMNA
SCHEMBL9310693 0.69 LMNA (0.32) LMNA
SCHEMBL5323459 0.67
SCHEMBL477040 0.67 LMNA (0.30) LMNA
SCHEMBL17292693 0.67 LMNA (0.30) LMNA
SCHEMBL6406502 0.64
SCHEMBL1899752 0.64
SCHEMBL34678 0.64
SCHEMBL6872536 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2766001-B1 BUFFERED OXYGEN THERAPEUTIC NUVOX PHARMA LLC (US) 2024-05-15 EP disclosed
US-8822549-B2 Buffered oxygen therapeutic NUVOX PHARMA LLC 2014-09-02 US disclosed
EP-2766001-A1 BUFFERED OXYGEN THERAPEUTIC Nuvox Pharma, LLC (US) 2014-08-20 EP disclosed
US-20130096204-A1 Buffered Oxygen Therapeutic NUVOX PHARMA LLC 2013-04-18 US disclosed
WO-2013056246-A1 BUFFERED OXYGEN THERAPEUTIC NUVOX PHARMA L.L.C. (US) 2013-04-18 WO disclosed
EP-1015039-B1 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP (US) 2008-08-27 EP disclosed
US-20070059248-A1 Oxygen delivery agents and uses for the same IMARX THERAPEUTICS, INC. 2007-03-15 US disclosed
US-7105151-B2 Oxygen delivery agents and uses for the same IMARX THERAPEUTICS, INC. (US) 2006-09-12 US disclosed
EP-1037673-B1 CHARGED LIPIDS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP (US) 2006-08-23 EP disclosed
EP-1039834-B1 OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE IMARX PHARMACEUTICAL CORP (US) 2005-09-28 EP disclosed
US-6028066-A FOR DELIVERING HIGHER CONCENTRATIONS OF BIOACTIVE AGENTS TO IMPROVE EFFICACY OF THE BIOACTIVE AGENTS IMARX PHARMACEUTICAL CORP. (US) 2000-02-22 US disclosed
WO-1999030620-A1 OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE IMARX PHARMACEUTICAL CORP. (US) 1999-06-24 WO disclosed
EP-0901793-A1 Thermal preactivation of gaseous precursor filled compositions IMARX PHARMACEUTICAL CORP. (US) 1999-03-17 EP disclosed
WO-1998057670-A1 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP. (US) 1998-12-23 WO disclosed
WO-1998051282-A1 SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME IMARX PHARMACEUTICAL CORP. (US) 1998-11-19 WO disclosed
WO-1998051284-A1 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP. (US) 1998-11-19 WO disclosed
WO-1998050040-A1 NOVEL LIPID SOLUBLE STEROID PRODRUGS IMARX PHARMACEUTICAL CORP. (US) 1998-11-12 WO disclosed
WO-1998050041-A1 NOVEL PRODRUGS COMPRISING FLUORINATED AMPHIPHILES IMARX PHARMACEUTICAL CORP. (US) 1998-11-12 WO disclosed
WO-1998042384-A1 METHODS FOR DELIVERING BIOACTIVE AGENTS IMARX PHARMACEUTICAL CORP. (US) 1998-10-01 WO disclosed
WO-1998042383-A1 CHARGED LIPIDS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP. (US) 1998-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096204-A1 Buffered Oxygen Therapeutic HIF1AN, HIF1A, FGB LMNA 1449/4885
US-20070059248-A1 Oxygen delivery agents and uses for the same VEGFA, PGF, SLCO2A1 LMNA 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.