Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656363 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL3267641 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL27492024 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL479710 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL2000689 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL157327 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL479450 | 1.00 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL479553 | 0.98 | CES2 (0.42) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL3788611 | 0.98 | CES2 (0.42) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL27902117 | 0.93 | CES2 (0.36) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732156-B2 | Method for adhering cured silicones to low energy plastics and composite prepared by the method | DOW SILICONES CORPORATION (US) | 2023-08-22 | — | — | US | claimed |
| EP-3601414-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | Dow Silicones Corporation (US) | 2020-02-05 | — | — | EP | claimed |
| US-20200032119-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DOW SILICONES CORPORATION | 2020-01-30 | — | — | US | claimed |
| WO-2018182950-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DOW SILICONES CORPORATION (US) | 2018-10-04 | — | — | WO | claimed |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | DOW SILICONES CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| EP-3898775-B1 | POLYFUNCTIONAL ORGANOSILOXANES, COMPOSITIONS CONTAINING SAME, AND METHODS FOR THE PREPARATION THEREOF | DOW SILICONES CORP (US) | 2025-03-12 | — | — | EP | disclosed |
| US-20250045834-A1 | ENVIRONMENTAL ATTRIBUTES FOR AQUEOUS POLYMERIC COMPOSITION | BASF SE (DE) | 2025-02-06 | — | — | US | disclosed |
| EP-4453837-A1 | ENVIRONMENTAL ATTRIBUTES FOR AQUEOUS POLYMERIC COMPOSITION | BASF SE (DE) | 2024-10-30 | — | — | EP | disclosed |
| EP-4212575-B1 | METHODS FOR MAKING POLYFUNCTIONAL ORGANOSILOXANES AND COMPOSITIONS CONTAINING SAME | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20240084076-A1 | METHODS FOR MAKING POLYFUNCTIONAL ORGANOSILOXANES AND COMPOSITIONS CONTAINING SAME | DOW SILICONES CORPORATION | 2024-03-14 | — | — | US | disclosed |
| US-11905375-B2 | Polyfunctional organosiloxanes, compositions containing same, and methods for the preparation thereof | DOW SILICONES CORPORATION (US) | 2024-02-20 | — | — | US | disclosed |
| EP-3673027-B1 | DUAL CURE ADHESIVE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE | DOW SILICONES CORP (US) | 2023-11-01 | — | — | EP | disclosed |
| US-20020195453-A1 | Fuel tanks and fuel transport lines | MCLEOD DAVID G (US) | 2002-12-26 | — | — | US | disclosed |
| EP-1244710-A1 | AMINE ORGANOBORANE COMPLEX POLYMERIZATION INITIATORS AND POLYMERIZABLE COMPOSITIONS | Dow Global Technologies Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20020058764-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GLOBAL TECHNOLOGIES LLC | 2002-05-16 | — | — | US | disclosed |
| US-20020033227-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GOBAL TECHNOLOGIES | 2002-03-21 | — | — | US | disclosed |
| US-20020031607-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW CHEMICAL COMPANY, THE | 2002-03-14 | — | — | US | disclosed |
| US-20020028894-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GLOBAL TECHNOLOGIES INC. | 2002-03-07 | — | — | US | disclosed |
| US-20020025381-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GLOBAL TECHNOLOGIES INC. | 2002-02-28 | — | — | US | disclosed |
| WO-2001044311-A1 | AMINE ORGANOBORANE COMPLEX POLYMERIZATION INITIATORS AND POLYMERIZABLE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11732156-B2 | Method for adhering cured silicones to low energy plastics and composite prepared by the method | DNMT3B, OXER1, MSMO1 | CES2 367/4885CES1 2021/4885HDAC8 2551/4885 |
| US-20200032119-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DNMT3B, OXER1, MSMO1 | CES2 367/4885CES1 2021/4885HDAC8 2551/4885 |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | HAO2, H1-2, HRH2 | CES2 597/4885CES1 1818/4885HDAC8 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.