Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648731 | 1.00 | KMT2A (0.39) | KMT2AKDM4EGAAMEN1S100A4 | |
| SCHEMBL4648906 | 0.89 | KMT2A (0.39) | KMT2AKDM4EGAAMEN1S100A4 | |
| SCHEMBL4648903 | 0.89 | KMT2A (0.39) | KMT2AKDM4EGAAMEN1S100A4 | |
| SCHEMBL4648045 | 0.80 | PTPRC (0.40) | KMT2AKDM4EGAAMEN1PTPRC | |
| Naftazone SCHEMBL4648800 | 0.80 | MEN1 (0.44) | KMT2AKDM4EGAAMEN1PTPRC | |
| Naftazone SCHEMBL1697156 | 0.80 | MEN1 (0.44) | KMT2AKDM4EGAAMEN1PTPRC | |
| Naftazone SCHEMBL29615756 | 0.80 | MEN1 (0.44) | KMT2AKDM4EGAAMEN1PTPRC | |
| SCHEMBL4648972 | 0.74 | PSMD14 (0.39) | KMT2AKDM4EGAAMEN1CA1 | |
| SCHEMBL4648976 | 0.74 | PSMD14 (0.39) | KMT2AKDM4EGAAMEN1CA1 | |
| SCHEMBL2525185 | 0.68 | PTPRC (0.52) | KMT2AKDM4EMEN1S100A4BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |