Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742507 | 0.91 | SLC6A4 (0.38) | OPRM1OPRL1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28692309 | 0.86 | CYP2A13 (0.36) | OPRM1OPRL1KDM4EALDH1A1 | |
| SCHEMBL31459234 | 0.86 | HDAC4 (0.43) | OPRM1OPRL1SLC6A4SLC6A3TSHR | |
| SCHEMBL5642482 | 0.86 | HDAC4 (0.43) | OPRM1OPRL1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31459378 | 0.86 | HDAC4 (0.43) | OPRM1OPRL1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31454418 | 0.86 | OPRM1 (0.33) | OPRM1OPRL1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14921048 | 0.80 | OPRM1 (0.37) | OPRM1OPRL1ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL1020364 | 0.79 | HDAC4 (0.48) | OPRL1KDM4EALDH1A1L3MBTL1SLC6A4 | |
| SCHEMBL31459475 | 0.78 | ADRA1A (0.41) | OPRM1OPRL1SLC6A4LMNATSHR | |
| SCHEMBL4555845 | 0.78 | ADRA1A (0.41) | OPRM1OPRL1SLC6A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859232-A | Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes | MONSANTO COMPANY (US) | 1989-08-22 | — | — | US | claimed |
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | 7TM PHARMA A/S (DK) | 2008-12-18 | — | — | US | disclosed |
| EP-1960376-A1 | OXADIAZOLE DERIVATIVES WITH CRTH2 RECEPTOR ACTIVITY | 7TM Pharma A/S (DK) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007062773-A1 | OXADIAZOLE DERIVATIVES WITH CRTH2 RECEPTOR ACTIVITY | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| US-4859232-A | Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes | MONSANTO COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | HRH2, HRH1, HRH3 | OPRM1 701/4885OPRL1 569/4885KDM4E 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.