Butadiene

Butadiene

SCHEMBL464883

C=CC=C.CC=C(C)C(=O)O.CC=C(C)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
PTGS1 P23219 1/20 0.36
AKR1C3 P42330 1/20 0.36
LMNA P02545 1/20 0.35
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL464974 1.00 ALDH1A1 (0.40) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Butadiene SCHEMBL501645 1.00 ALDH1A1 (0.40) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Butadiene SCHEMBL17699118 0.95 ALDH1A1 (0.36) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Propene SCHEMBL7932633 0.91 ALDH1A1 (0.42) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Fumaric Acid SCHEMBL9402867 0.90 TSHR (0.43) ALDH1A1PTGS1AKR1C3LMNA
Ethylene SCHEMBL6419930 0.88 PTGS1 (0.39) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Ethylene SCHEMBL21712506 0.88
Ethylene SCHEMBL6419933 0.88 PTGS1 (0.39) ALDH1A1PTGS1AKR1C3LMNAFFAR3
Ethylene SCHEMBL418570 0.88
SCHEMBL1396002 0.87 FFAR3 (0.43) ALDH1A1PTGS1AKR1C3LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3566693-B1 EYE DEVICE EYED PHARMA (BE) 2021-02-17 EP claimed
EP-3566693-A1 EYE DEVICE EyeD Pharma (BE) 2019-11-13 EP claimed
EP-3068372-B1 EYE DEVICE EYED PHARMA (BE) 2019-05-08 EP claimed
US-9999595-B2 Eye device EYED PHARMA (BE) 2018-06-19 US claimed
US-20160287513-A1 EYE DEVICE EYED PHARMA (BE) 2016-10-06 US claimed
EP-3068372-A1 EYE DEVICE EyeD Pharma (BE) 2016-09-21 EP claimed
WO-2015071427-A1 EYE DEVICE EYED PHARMA (BE) 2015-05-21 WO claimed
US-12006460-B2 Photoelectric conversion compound and photoelectric conversion composition including the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-06-11 US disclosed
WO-2023161401-A1 EYELET EYED PHARMA (BE) 2023-08-31 WO disclosed
EP-4233836-A1 INTRAOCULAR DRUG DELIVERY DEVICE COMPRISING AN EYELET Eyed Pharma (BE) 2023-08-30 EP disclosed
US-20230212455-A1 PHOTOELECTRIC CONVERSION COMPOUND AND PHOTOELECTRIC CONVERSION COMPOSITION INCLUDING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-07-06 US disclosed
EP-3566693-B1 EYE DEVICE EYED PHARMA (BE) 2021-02-17 EP disclosed
EP-3566693-A1 EYE DEVICE EyeD Pharma (BE) 2019-11-13 EP disclosed
EP-1920005-B1 EPOXY COMPOSITIONS HAVING IMPROVED IMPACT RESISTANCE HENKEL AG & CO KGAA (DE) 2011-11-23 EP disclosed
US-7919555-B2 improve adhesion of the cured adhesive to oily metal substrates, improve peel strength at low temperatures; epoxy resins, polymers with shell-core, auxiliary impact modifier/toughening agent, methylguanidine curing agent; a block terpolymer of butadiene-methyl methacrylate-styrene HENKEL AG & CO. KGAA (DE) 2011-04-05 US disclosed
US-20090104448-A1 PREFORMED ADHESIVE BODIES USEFUL FOR JOINING SUBSTRATES HENKEL AG & CO. KGAA (DE) 2009-04-23 US disclosed
WO-2008151946-A1 ADHESIVE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2008-12-18 WO disclosed
US-20080188609-A1 EPOXY COMPOSITIONS HAVING IMPROVED IMPACT RESISTANCE HENKEL AG & CO. KGAA (DE) 2008-08-07 US disclosed
EP-1589070-B1 Polymer composition with improved stiffness and impact strength BOREALIS TECH OY (FI) 2008-03-12 EP disclosed
EP-1589070-A1 Polymer composition with improved stiffness and impact strength Borealis Technology OY (FI) 2005-10-26 EP disclosed