Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289573 | 0.73 | PI4KA (0.39) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5034300 | 0.71 | ADORA2A (0.46) | PI4KAPI4K2BPI4K2API4KBEHMT1 | |
| SCHEMBL2293030 | 0.69 | RXFP1 (0.42) | RXFP1 | |
| SCHEMBL3368304 | 0.68 | ADORA2A (0.40) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL19778463 | 0.64 | ADK (0.48) | RXFP1AHCYPI4KAPI4K2BPI4K2A | |
| SCHEMBL13773372 | 0.64 | BCHE (0.54) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20624558 | 0.64 | ADORA2A (0.51) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9120633 | 0.63 | EHMT1 (0.47) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL25390947 | 0.63 | TAS1R3 (0.39) | RXFP1P2RY1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27592100 | 0.63 | ADORA2A (0.48) | AHCYPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |