Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ATG7 | O95352 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293030 | 0.78 | RXFP1 (0.42) | RXFP1ATG7 | |
| SCHEMBL2291620 | 0.78 | TRPM2 (0.40) | — | |
| SCHEMBL9851782 | 0.77 | PI4KA (0.31) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4649016 | 0.73 | RXFP1 (0.40) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9851849 | 0.71 | — | — | |
| SCHEMBL7893477 | 0.70 | ADORA3 (0.44) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL9548680 | 0.69 | ADORA3 (0.37) | PI4KAPI4K2BPI4K2API4KBCYP1A2 | |
| SCHEMBL9218681 | 0.69 | ADORA1 (0.44) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL25389129 | 0.69 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL9548802 | 0.69 | ADORA2A (0.42) | PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | PI4KA 4490/4885PI4K2B 3867/4885PI4K2A 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.