Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.67 |
| ▸ | BACE1 | P56817 | 7/20 | 0.67 |
| ▸ | BCHE | P06276 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | EEF2K | O00418 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | CCR3 | P51677 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278559 | 1.00 | ACHE (0.67) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL2279311 | 0.91 | KDM4E (0.66) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL4230587 | 0.87 | KDM4E (0.60) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL4225304 | 0.81 | MCHR1 (0.54) | KDM4EGAASIGMAR1DRD2DRD4 | |
| SCHEMBL330905 | 0.81 | ALDH1A1 (0.63) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL330906 | 0.81 | ALDH1A1 (0.63) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL13419693 | 0.81 | KDM4E (0.74) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL4229449 | 0.81 | SIGMAR1 (0.53) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL4229453 | 0.81 | SIGMAR1 (0.53) | ACHEBACE1BCHEKDM4EGAA | |
| SCHEMBL13419300 | 0.80 | GAA (0.72) | ACHEBACE1BCHEKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685102-A4 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1685102-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047251-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |