Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857045 | 0.85 | TAAR1 (0.42) | ALDH1A1TAAR1LOXL2DPP4 | |
| SCHEMBL1398129 | 0.77 | DPP4 (0.36) | TAAR1LOXL2DPP4 | |
| SCHEMBL1398120 | 0.76 | TAAR1 (0.37) | ALDH1A1TAAR1LOXL2DPP4 | |
| SCHEMBL30350528 | 0.74 | TAAR1 (0.36) | ALDH1A1TAAR1LOXL2DPP4 | |
| SCHEMBL15819889 | 0.74 | TAAR1 (0.36) | ALDH1A1TAAR1LOXL2DPP4 | |
| SCHEMBL24959625 | 0.74 | TAAR1 (0.45) | ALDH1A1TAAR1 | |
| SCHEMBL21021423 | 0.74 | RIPK1 (0.36) | ALDH1A1 | |
| SCHEMBL25417050 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL15819455 | 0.72 | TAAR1 (0.65) | ALDH1A1TAAR1 | |
| SCHEMBL29467951 | 0.72 | TAAR1 (0.41) | ALDH1A1TAAR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293749-A1 | Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position | GRUENENTHAL GMBH (DE) | 2008-11-27 | — | — | US | disclosed |
| EP-1957481-A1 | PYRROLIDIN(THI)ONES HETEROCYCLICALLY SUBSTITUTED IN 3-POSITION | Grünenthal GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007062817-A1 | PYRROLIDIN(THI)ONES HETEROCYCLICALLY SUBSTITUTED IN 3-POSITION | Grünenthal GmbH (DE) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293749-A1 | Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position | TPMT, MALT1, THPO | ALDH1A1 2211/4885TAAR1 2287/4885LOXL2 4161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.