Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649158 | 0.85 | ALDH1A1 (0.41) | TAAR1LOXL2ALDH1A1DPP4 | |
| SCHEMBL1398120 | 0.85 | TAAR1 (0.37) | TAAR1LOXL2ALDH1A1DPP4IDO1 | |
| SCHEMBL24959625 | 0.83 | TAAR1 (0.45) | TAAR1ALDH1A1 | |
| SCHEMBL30350528 | 0.83 | TAAR1 (0.36) | TAAR1LOXL2ALDH1A1DPP4HTR2A | |
| SCHEMBL15819889 | 0.83 | TAAR1 (0.36) | TAAR1LOXL2ALDH1A1DPP4HTR2A | |
| SCHEMBL29467951 | 0.80 | TAAR1 (0.41) | TAAR1LOXL2ALDH1A1HTR2A | |
| SCHEMBL15819455 | 0.80 | TAAR1 (0.65) | TAAR1ALDH1A1HTR2AHTR2C | |
| SCHEMBL13527771 | 0.80 | LOXL2 (0.42) | TAAR1LOXL2HTR2A | |
| SCHEMBL1764730 | 0.78 | TAAR1 (0.39) | TAAR1DPP4IDO1HTR2AHTR2C | |
| SCHEMBL856734 | 0.78 | TAAR1 (0.39) | TAAR1IDO1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431155-A | Method for synthesizing 2,4, 6-trifluoro-benzylamine by one-pot method | 浙江永太科技股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-115015310-B | Analysis method of sulfhydryl compound | 宁波大学 | 2024-12-10 | — | — | CN | claimed |
| US-12037343-B2 | Process for the preparation of sodium (2r,5s,13ar)-7,9-dioxo-10-((2,4,6,-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13A-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-B] [1,3] oxazepin-8-olate and its polymorphic form | HONOUR LAB LIMITED (IN) | 2024-07-16 | — | — | US | claimed |
| CN-117185935-A | Method for preparing 2,4, 6-trifluoro-benzylamine by catalytic hydrogenation | 大连奇凯医药科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-110963922-B | Preparation method of 2,4, 6-trifluoro-benzylamine | 成都博腾药业有限公司 | 2023-09-05 | — | — | CN | claimed |
| US-20230219977-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | HONOUR LAB LIMITED (IN) | 2023-07-13 | — | — | US | claimed |
| CN-115015310-A | Analytical method of sulfhydryl compound | 宁波大学 | 2022-09-06 | — | — | CN | claimed |
| CN-112457197-B | Preparation method of compound 2, 4, 6-trifluorobenzylamine | 浙江丽晶化学有限公司 | 2022-05-13 | — | — | CN | claimed |
| US-20210363158-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | HONOUR LAB LIMITED (IN) | 2021-11-25 | — | — | US | claimed |
| CN-112457197-A | Preparation method of compound 2, 4, 6-trifluorobenzylamine | 浙江丽晶化学有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-107778183-B | Preparation method of 2,4, 6-trifluorobenzylamine | 杭州澳赛诺生物科技有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-110819338-A | Composite fluorescent particle protected by super-hydrophobic shell layer and preparation method thereof | 重庆大学 | 2020-02-21 | — | — | CN | claimed |
| US-20200035418-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES | 2020-01-30 | — | — | US | claimed |
| CN-110683959-A | Synthetic method of 2,4, 6-trifluorobenzylamine | 浙江中欣氟材股份有限公司 | 2020-01-14 | — | — | CN | claimed |
| WO-2020007032-A1 | METHOD FOR SYNTHESIZING 2,4,6-TRIFLUOROBENZYLAMINE | 浙江中欣氟材股份有限公司 | 2020-01-09 | — | — | WO | claimed |
| WO-2018152494-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES (US) | 2018-08-23 | — | — | WO | claimed |
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | ELEXOPHARM GMBH (DE) | 2016-11-03 | — | — | US | claimed |
| US-8729089-B2 | Pyrido(3,2-d)pyrimidines useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2014-05-20 | — | — | US | claimed |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | HSD17B1, HSD17B2, HSD17B3 | TAAR1 3770/4885LOXL2 2109/4885ALDH1A1 68/4885 |
| US-20210363158-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | OXER1, CYP4Z1, CYP4A11 | TAAR1 710/4885LOXL2 2093/4885ALDH1A1 671/4885 |
| US-12037343-B2 | Process for the preparation of sodium (2r,5s,13ar)-7,9-dioxo-10-((2,4,6,-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13A-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-B] [1,3] oxazepin-8-olate and its polymorphic form | OXER1, OR10J3, CYP2A13 | TAAR1 775/4885LOXL2 1875/4885ALDH1A1 577/4885 |
| US-20230219977-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | OXER1, CYP26B1, OR10J3 | TAAR1 681/4885LOXL2 1565/4885ALDH1A1 777/4885 |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, DPYD, PNP | TAAR1 965/4885LOXL2 2266/4885ALDH1A1 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.