Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649341 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL307045 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL859321 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302136 | 0.74 | MAPK1 (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Fluoride SCHEMBL27660671 | 0.74 | MAPK1 (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL28375708 | 0.74 | TSHR (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302663 | 0.73 | KCNN4 (0.45) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302768 | 0.72 | TSHR (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302535 | 0.72 | ALDH1A1 (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3091188 | 0.71 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138698-A1 | SYNTHESIS OF BETA-MANNURONIC ACID OLIGOSACCHARIDES | ANCORA PHARMACEUTICALS INC. (US) | 2012-10-11 | — | — | WO | claimed |
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2012138698-A1 | SYNTHESIS OF BETA-MANNURONIC ACID OLIGOSACCHARIDES | ANCORA PHARMACEUTICALS INC. (US) | 2012-10-11 | — | — | WO | disclosed |
| EP-0229384-B1 | Beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5134231-A | Chemical intermediates for 1-alkylcarbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0229384-A2 | Beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-07-22 | — | — | EP | disclosed |