SCHEMBL4649359

SCHEMBL4649359

CC1OC(=O)NN=C1c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 19/20 0.71
PDE3A Q14432 19/20 0.71
GPR119 Q8TDV5 1/20 0.62
PDE4A P27815 1/20 0.53
PDE4B Q07343 1/20 0.53
PDE4C Q08493 1/20 0.53
PDE4D Q08499 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20702942 0.83 PDE3B (1.00) PDE3BPDE3AGPR119PDE4APDE4B
SCHEMBL2583119 0.78 GPR119 (1.00) GPR119
SCHEMBL212810 0.78 CA2 (0.50) PDE3BPDE3AGPR119PDE4APDE4B
SCHEMBL9253775 0.76 PDE3B (0.62) PDE3BPDE3AGPR119PDE4APDE4B
SCHEMBL20705316 0.76 PDE3B (0.64) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL20702632 0.75 PDE3B (1.00) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL26363929 0.74 PDE3B (0.69) PDE3BPDE3AGPR119PDE4APDE4B
SCHEMBL30882502 0.74 PDE3B (0.59) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL30882608 0.73 PDE3B (0.66) PDE3BPDE3AGPR119PDE4APDE4B
SCHEMBL30882456 0.73 PDE3B (0.67) PDE3BPDE3AGPR119PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963432-A1 EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS General Electric Company (US) 2008-09-03 EP disclosed
WO-2007078737-A1 EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS GENERAL ELECTRIC COMPANY (US) 2007-07-12 WO disclosed
US-20070149629-A1 Expanded and expandable high glass transition temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 US disclosed
EP-0181000-A2 Foamable polyetherimide resin formulation GENERAL ELECTRIC COMPANY (US) 1986-05-14 EP disclosed
US-4543368-A DIHYDRODIAZINONE BLOWING AGENT GENERAL ELECTRIC COMPANY (US) 1985-09-24 US disclosed
US-4334030-A INJECTION MOLDABLE CONCENTRATES CONTAINING AMIDE DERIVATIVES OF AZODICARBOXYLIC ACID AND A DIHYDROOXADIAZINONE AS BLOWING AGENTS GENERAL ELECTRIC COMPANY (US) 1982-06-08 US disclosed
US-4163037-A USING A DIHYDROOXADIAZINONE BLOWING AGENT, INJECTION MOLDING GENERAL ELECTRIC COMPANY (US) 1979-07-31 US disclosed
US-4160088-A HALOGENATION OF KETONE, ALKANOL, HYDROLYSIS GENERAL ELECTRIC COMPANY (US) 1979-07-03 US disclosed
US-4158094-A BLOWING AGENTS GENERAL ELECTRIC COMPANY (US) 1979-06-12 US disclosed
US-4097671-A 5-PHENYL-3,6-DIHYDRO-1,3,4-OXADIAZIN-2-ONE, THERMOPLASTIC POLYMER BLOWING AGENT GENERAL ELECTRIC COMPANY (US) 1978-06-27 US disclosed
US-4097425-A POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE GENERAL ELECTRIC COMPANY (US) 1978-06-27 US disclosed