Biphenyl

Biphenyl

SCHEMBL4649459

O=C1c2ccccc2C(=O)N1S(=O)(=O)N1C(=O)c2ccccc2C1=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 2/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
THRB P10828 1/20 0.44
XBP1 P17861 1/20 0.44
PTBP1 P26599 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31229117 0.91 CASP3 (0.48) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL8452187 0.91 CASP3 (0.48) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL7993799 0.83 NR1H2 (0.42) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL28902435 0.75 NR1H2 (0.46) KMT2AMAPTALDH1A1MEN1LMNA
SCHEMBL12591511 0.74 CASP3 (0.47) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL11424876 0.74 PARL (0.59) KMT2AMAPTALDH1A1KDM4EHPGD
Anthraquinone SCHEMBL27283959 0.73 MEN1 (0.75) KMT2AMAPTALDH1A1KDM4EMEN1
SCHEMBL1918743 0.73 KMT2A (0.47) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL115715 0.73 CASP3 (0.50) KMT2AMAPTALDH1A1KDM4EHPGD
SCHEMBL21034093 0.73 CASP3 (0.45) KMT2AMAPTALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963433-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS General Electric Company (US) 2008-09-03 EP claimed
EP-1960470-A2 FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS General Electric Company (US) 2008-08-27 EP claimed
WO-2008091253-A1 HIGH HEAT ELECTRICAL CONNECTORS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-31 WO claimed
WO-2007078788-A2 FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS GENERAL ELECTRIC COMPANY (US) 2007-07-12 WO claimed
WO-2007075365-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-07-05 WO claimed
US-20070142569-A1 Food service articles of manufacture comprising high temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-21 US claimed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed