Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146789 | 0.84 | NPC1 (0.66) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6048619 | 0.82 | MEN1 (0.58) | MAPTNPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL2203164 | 0.81 | NPC1 (0.79) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7979973 | 0.80 | RAB9A (0.57) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16541365 | 0.80 | CA12 (0.49) | MAPTNPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL17073991 | 0.79 | NPC1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1008979 | 0.78 | LTA4H (0.55) | CYP1A2ESR1ESR2MEN1KMT2A | |
| SCHEMBL9750796 | 0.78 | L3MBTL1 (0.51) | MAPTNPC1KDM4EESR1ESR2 | |
| SCHEMBL6048620 | 0.78 | NR5A1 (0.67) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6048615 | 0.78 | NR5A1 (0.67) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |