Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649624 | 0.84 | CNR2 (0.42) | CNR2CHEK1NTRK1FYNRET | |
| SCHEMBL4649631 | 0.83 | CNR2 (0.56) | CNR2CDK5POLB | |
| SCHEMBL4649692 | 0.82 | CNR2 (0.50) | CNR2CHEK1NTRK1FYNRET | |
| SCHEMBL4649071 | 0.82 | CNR2 (0.37) | CNR2FLT3JAK3CYP1A2CYP2C9 | |
| SCHEMBL4649780 | 0.82 | CNR2 (0.37) | CNR2CHEK1NTRK1FYNRET | |
| SCHEMBL4649776 | 0.80 | CNR2 (0.50) | CNR2CHRNB4CHRNA3KMOEPHA2 | |
| SCHEMBL4650258 | 0.78 | CNR2 (0.33) | CNR2 | |
| SCHEMBL4648963 | 0.78 | KDM4E (0.46) | CNR2POLBMEN1ALDH1A1MAPT | |
| SCHEMBL4649736 | 0.76 | CDK4 (0.38) | CNR2POLBL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL4650342 | 0.75 | CNR2 (0.45) | CNR2CHRNB4CHRNA3KMOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718613-B1 | PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2008-09-03 | — | — | EP | disclosed |