Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447707 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL29837196 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL1026013 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL1027549 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL1026402 | 0.86 | ALDH1A1 (0.56) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL13885266 | 0.84 | ALDH1A1 (0.42) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL4544532 | 0.83 | MAPK1 (0.50) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL11654910 | 0.83 | GPR35 (0.50) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL7030336 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GPR35MAPK1HPGDTSHR | |
| SCHEMBL28238083 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GPR35MAPK1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895985-B1 | Method for producing 2,2-bis(3-amino-4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropane | NIPPON KAYAKU KK (JP) | 2003-02-05 | — | — | EP | claimed |
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | claimed |
| WO-1994012465-A1 | POLYAMIDES AND POLYPYRROLONES FOR FLUID SEPARATION MEMBRANES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-06-09 | — | — | WO | claimed |
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | claimed |
| US-4978808-A | NITRATION OF 2,2-BIS/P-HYDROXYPHENYL/HEXAFLUOROPROPANE WITH NITRIC ACID IN A LOW FATTY ACID | CENTRAL GLASS COMPANY, LIMITED (JP) | 1990-12-18 | — | — | US | claimed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | claimed |
| JP-6211752-A | — | — | None | — | — | JP | disclosed |
| CN-105712885-B | A kind of process for refining of bis- (3- nitro -4- hydroxy phenyls) hexafluoropropane of 2,2- | 连云港市泰卓新材料有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105753710-A | Environmentally friendly preparation technology of 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane | 连云港市泰卓新材料有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-105753710-A | Environmentally friendly preparation technology of 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane | 连云港市泰卓新材料有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-101643427-B | Preparation method of 2,2-bis(3-amino-4-hydroxylphenyl)hexafluoropropane | DAJUN CHENG | 2012-09-26 | — | — | CN | disclosed |
| CN-101643427-A | Preparation method of 2,2-bis(3-amino-4-hydroxylphenyl)hexafluoropropane | DAJUN CHENG | 2010-02-10 | — | — | CN | disclosed |
| EP-1245635-B1 | FLUOROELASTOMER COMPOSITION FOR CROSSLINKING | DAIKIN IND LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-4978808-A | NITRATION OF 2,2-BIS/P-HYDROXYPHENYL/HEXAFLUOROPROPANE WITH NITRIC ACID IN A LOW FATTY ACID | CENTRAL GLASS COMPANY, LIMITED (JP) | 1990-12-18 | — | — | US | disclosed |
| EP-0254990-B1 | PROCESS FOR PREPARING 2,2-BIS-(4-HYDROXY-3-NITROPHENYL)-HEXAFLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0254990-B1 | PROCESS FOR PREPARING 2,2-BIS-(4-HYDROXY-3-NITROPHENYL)-HEXAFLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0291778-A1 | Process for the preparation of high temperature-resistant dielectrics | SIEMENS AKTIENGESELLSCHAFT (DE) | 1988-11-23 | — | — | EP | disclosed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |
| EP-0254990-A1 | Process for preparing 2,2-bis-(4-hydroxy-3-nitrophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0254990-A1 | Process for preparing 2,2-bis-(4-hydroxy-3-nitrophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |