Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319069 | 0.92 | KCNMA1 (0.49) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL1027549 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL31447707 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL1026013 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL4649869 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL29837196 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL6823350 | 0.85 | GPR35 (0.56) | ALDH1A1MAPK1HPGDTSHRGPR35 | |
| SCHEMBL1024910 | 0.85 | GPR35 (0.56) | ALDH1A1MAPK1HPGDTSHRGPR35 | |
| SCHEMBL11654910 | 0.83 | GPR35 (0.50) | ALDH1A1MAPK1HPGDTSHRTP53 | |
| SCHEMBL4544532 | 0.83 | MAPK1 (0.50) | ALDH1A1MAPK1HPGDTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059850-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | UNIVERSIDAD DE CÁDIZ (ES) | 2011-03-10 | — | — | US | claimed |
| US-7807821-B1 | Method for the synthesis of nucleic acid without protecting base moiety | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-05 | — | — | US | claimed |
| EP-2048136-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | Universidad de Cadiz (ES) | 2009-04-15 | — | — | EP | claimed |
| EP-1721908-A1 | NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES | Japan Science and Technology Agency (JP) | 2006-11-15 | — | — | EP | claimed |
| JP-52131539-A | — | — | None | — | — | JP | disclosed |
| US-12403144-B2 | HECT E3 ligase inhibitors and uses thereof | IFOM —FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE (IT) | 2025-09-02 | — | — | US | disclosed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| CN-118388379-A | Organic total synthesis method of nimesulide derivative | 大连理工大学 | 2024-07-26 | — | — | CN | disclosed |
| US-20240051952-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-02-15 | — | — | US | disclosed |
| EP-3976185-B1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | IFOM ST FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS (IT) | 2024-02-14 | — | — | EP | disclosed |
| US-4225731-A | Process for the preparation of trifluoromethylphenols | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4180572-A | Lipogenesis control by esters of benzoxazinecarboxylic acids | SHELL OIL COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4164576-A | LIPOGENESIS INHIBITORS IN MAMMALS | SHELL OIL COMPANY (US) | 1979-08-14 | — | — | US | disclosed |
| EP-0000542-A1 | Process for the preparation of trifluoromethyl phenols | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| JP-S52131539-A | PHENOXYPHENOXYPROPIONIC ACID DERIVATIVES AND HERBICIDES | ISHIHARA SANGYO KAISHA LTD | 1977-11-04 | — | — | JP | disclosed |
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-3941832-A | Oxime ethers and pesticidal preparations containing them | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
| US-3941839-A | HERBICIDE | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12403144-B2 | HECT E3 ligase inhibitors and uses thereof | NEDD4, ITCH, UBE3A | ALDH1A1 2114/4885MAPK1 3151/4885HPGD 3455/4885 |
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | ALDH1A1 332/4885MAPK1 3619/4885HPGD 8/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | ALDH1A1 223/4885MAPK1 2789/4885HPGD 9/4885 |
| US-20240051952-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, QSOX1 | ALDH1A1 266/4885MAPK1 2914/4885HPGD 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.