Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.57 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518463 | 0.90 | MGLL (0.53) | MGLLKMT2AMAOBKDM4EMAPT | |
| SCHEMBL16744460 | 0.82 | MGLL (0.76) | MGLLKMT2AMAOBKDM4EMAPT | |
| SCHEMBL4649907 | 0.81 | MGLL (0.62) | MGLLKMT2ACACNA2D1CACNA1BCACNB1 | |
| SCHEMBL27545187 | 0.80 | KMT2A (0.74) | MGLLKMT2AMAOBKDM4EMAPT | |
| SCHEMBL4678831 | 0.79 | SIGMAR1 (0.51) | MGLLKMT2AMEN1 | |
| SCHEMBL28015720 | 0.79 | ALDH1A1 (0.47) | MGLLKDM4EALDH1A1 | |
| SCHEMBL4013471 | 0.79 | KMT2A (0.67) | MGLLKMT2AMAOBKDM4EMAPT | |
| SCHEMBL4275831 | 0.78 | NPC1 (0.71) | KMT2AMAOBNPSR1ALDH1A1CACNA2D1 | |
| SCHEMBL13994872 | 0.77 | KMT2A (1.00) | MGLLKMT2AMAOBKDM4EMAPT | |
| SCHEMBL917665 | 0.77 | KMT2A (0.70) | MGLLKMT2AMAOBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019676-A2 | METHOD FOR INCREASING THE BIOAVAILABILITY OF BENZHYDRYL PIPERAZINE CONTAINING COMPOUNDS | Neuromed Pharmaceuticals, Ltd. (CA) | 2009-02-04 | — | — | EP | claimed |
| WO-2007133481-A2 | METHOD FOR INCREASING THE BIOAVAILABILITY OF BENZHYDRYL PIPERAZINE CONTAINING COMPOUNDS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-11-22 | — | — | WO | claimed |