Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51416 | 0.76 | CYP2A6 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL29870578 | 0.76 | CYP2A6 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL29930545 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL3836747 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL30366237 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL3254994 | 0.71 | POLB (0.56) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL5950474 | 0.71 | ALDH1A1 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL5694926 | 0.71 | ALDH1A1 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL590476 | 0.71 | PTPN22 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL5950477 | 0.71 | TSHR (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969019-A1 | SURFACE-MODIFIED POLYMERIZATION CATALYSTS FOR THE PREPARATION OF LOW-GEL POLYOLEFIN FILMS | Borealis Technology OY (FI) | 2008-09-17 | — | — | EP | disclosed |
| WO-2008043388-A1 | SURFACE-MODIFIED POLYMERIZATION CATALYSTS FOR THE PREPARATION OF LOW-GEL POLYOLEFIN FILMS | BOREALIS TECHNOLOGY OY (FI) | 2008-04-17 | — | — | WO | disclosed |