Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870578 | 1.00 | CYP2A6 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL22555264 | 0.94 | CYP2A6 (0.54) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL29697719 | 0.83 | CYP2A6 (0.42) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL4650232 | 0.76 | CYP2A6 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL30366237 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL3836747 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL449348 | 0.75 | CYP2A6 (1.00) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL29930545 | 0.75 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL11476794 | 0.73 | CYP2A6 (0.95) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL8726153 | 0.71 | CYP2A6 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222654-A | KRAS G12C inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113054107-B | Organic solution combination for coating organic solar cell | 广州追光科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113054107-A | Organic solution combination for coating organic solar cell | 广州追光科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10793584-B2 | Naphthobischalcogenadiazole derivative and production method therefor | OSAKA UNIVERSITY (JP) | 2020-10-06 | — | — | US | disclosed |
| US-20190337966-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | OSAKA UNIVERSITY (JP) | 2019-11-07 | — | — | US | disclosed |
| US-8129554-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090118453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-5114896-A | Reaction product of magnesium, halogenated hydrocarbon, alkoxy compound, titanium compound, halogen-containing alcohol and solid halogenated hydrocarbon | TONEN CORPORATION (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0440813-A1 | METHOD OF PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793584-B2 | Naphthobischalcogenadiazole derivative and production method therefor | CYP24A1, CYP26B1, CYP21A2 | CYP2A6 96/4885ALDH1A1 600/4885HSD17B10 947/4885 |
| US-20190337966-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | CYP24A1, CYP26B1, CYP21A2 | CYP2A6 96/4885ALDH1A1 600/4885HSD17B10 947/4885 |
| US-20090118453-A1 | METAL COMPLEXES | SOD1, AP1M1, AP2M1 | CYP2A6 2496/4885ALDH1A1 366/4885HSD17B10 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.