SCHEMBL4650258

SCHEMBL4650258

CC(C)c1cc(Nc2cc(F)cc(F)c2)ncc1CN(C)C1CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649780 0.97 CNR2 (0.37) CNR2
SCHEMBL4649071 0.86 CNR2 (0.37) CNR2
SCHEMBL4648963 0.81 KDM4E (0.46) CNR2
SCHEMBL4649736 0.80 CDK4 (0.38) CNR2
SCHEMBL4649775 0.78 CNR2 (0.40) CNR2
SCHEMBL4649631 0.78 CNR2 (0.56) CNR2
SCHEMBL4649170 0.77 CNR2 (0.55) CNR2
SCHEMBL4650260 0.77 CNR2 (0.41) CNR2
SCHEMBL4649781 0.76 CNR2 (0.46) CNR2
SCHEMBL4649712 0.74 CNR2 (0.54) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718613-B1 PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS GLAXO GROUP LTD (GB) 2008-09-03 EP disclosed