Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445843 | 0.78 | PDK1 (0.38) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL3445845 | 0.78 | PDK1 (0.38) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL12317693 | 0.76 | CA2 (0.37) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL17979960 | 0.76 | CA1 (0.46) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL30360667 | 0.76 | CA1 (0.46) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL27772530 | 0.75 | CA1 (0.43) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL27641846 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL25541474 | 0.73 | CA1 (0.42) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL30530486 | 0.71 | ALDH1A1 (0.41) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL25620367 | 0.71 | CA1 (0.41) | CA1CA2CA5ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966188-A1 | ENANTIOSELECTIVE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS | Ratiopharm GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007079784-A1 | ENANTIOSELECTIVE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS | RATIOPHARM GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |