SCHEMBL4650737

SCHEMBL4650737

N#CC1(c2ccccc2)COCCO1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.37
ADRA1D P25100 1/20 0.34
OPRD1 P41143 1/20 0.31
OPRM1 P35372 1/20 0.31
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24604444 0.76 OPRM1 (0.35) OPRD1OPRM1
SCHEMBL138441 0.72 HTR2A (0.41) OPRM1
SCHEMBL2478984 0.71 HTR1A (0.44) HTR1AADRA1D
SCHEMBL1414768 0.69 HTR1A (0.43) HTR1AADRA1D
SCHEMBL25153966 0.69 OPRM1 (0.45) OPRD1OPRM1
SCHEMBL2382380 0.68 HTR1A (0.39) HTR1AADRA1DBACE1
SCHEMBL28061485 0.68 HTR1A (0.42) HTR1AADRA1DOPRM1BACE1
SCHEMBL28216267 0.68 HTR1A (0.39) HTR1AADRA1DBACE1
SCHEMBL11711562 0.67 OPRM1 (0.43) OPRD1OPRM1
SCHEMBL23886643 0.67 OPRM1 (0.32) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62091584-A None JP disclosed
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
CN-100365096-C Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2008-01-30 CN disclosed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed
CN-1753969-A Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2006-03-29 CN disclosed
EP-1599562-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES Nemoptic (FR) 2005-11-30 EP disclosed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US disclosed
US-4490276-A Liquid crystal admixtures including chloro-cyanophenyl substituted benzoates MERECK PATENT, GMBH FRANKFURTER STRASSE 250, 6100 DARMSTADT A COMPANY OF GERMANY 1984-12-25 US disclosed
US-4356104-A LIQUID CRYSTALS, ELECTROOPTICAL DISPLAY TIMEX CORPORATION (US) 1982-10-26 US disclosed
US-4356104-A LIQUID CRYSTALS, ELECTROOPTICAL DISPLAY TIMEX CORPORATION (US) 1982-10-26 US disclosed
US-4325830-A Three ring dioxane liquid crystalline compounds TIMEX CORPORATION (US) 1982-04-20 US disclosed
US-4325830-A Three ring dioxane liquid crystalline compounds TIMEX CORPORATION (US) 1982-04-20 US disclosed
US-4323504-A Cyclohexyl cyclohexyl dioxane liquid crystalline compounds and admixture containing same TIMEX CORPORATION (US) 1982-04-06 US disclosed
US-4323473-A Cyclohexyl cyclohexyl dioxane liquid crystalline compounds and admixture containing same TIMEX CORPORATION (US) 1982-04-06 US disclosed
US-4313878-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-02-02 US disclosed
US-4313878-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-02-02 US disclosed
US-4200580-A Dioxanylphenyl benzoate liquid crystal compounds TIMEX CORPORATION (US) 1980-04-29 US disclosed