Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493979 | 1.00 | KDM4E (0.36) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL9493973 | 1.00 | KDM4E (0.36) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL9174206 | 0.94 | GAA (0.35) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL10532005 | 0.94 | GAA (0.35) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL10613253 | 0.91 | GAA (0.36) | RAB9ACYP2C9MAPTCHRNB2CHRNA4 | |
| SCHEMBL4650916 | 0.90 | KDM4E (0.38) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL15255890 | 0.89 | KDM4E (0.37) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL27878839 | 0.89 | KDM4E (0.37) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL9513829 | 0.88 | CYP2C9 (0.36) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 | |
| SCHEMBL9639406 | 0.85 | CHRNB2 (0.48) | KDM4ERAB9AL3MBTL1CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384066-A | Free of nitriles, high holding ration (HR), liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-01-24 | — | — | US | disclosed |
| US-5356557-A | Electrooptical system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-10-18 | — | — | US | disclosed |