Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.86 |
| ▸ | HPGD | P15428 | 7/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.86 |
| ▸ | CA12 | O43570 | 3/20 | 0.86 |
| ▸ | CA1 | P00915 | 3/20 | 0.86 |
| ▸ | CA2 | P00918 | 3/20 | 0.86 |
| ▸ | CA7 | P43166 | 3/20 | 0.86 |
| ▸ | CA9 | Q16790 | 3/20 | 0.86 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.86 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.86 |
| ▸ | CA4 | P22748 | 1/20 | 0.86 |
| ▸ | CA6 | P23280 | 1/20 | 0.86 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.86 |
| ▸ | LIG1 | P18858 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL7614996 | 1.00 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL28844925 | 0.98 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL8001218 | 0.95 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL3450029 | 0.95 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL27592487 | 0.93 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL29360246 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL29362663 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL1509155 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL1967 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL8433746 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1573685-A4 | SECURE POINT OF SALE IMAGEABLE SUBSTRATE | APPLETON PAPER INC (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1352195-A4 | ULTRAVIOLET FILTER COATING | MITSUBISHI CHEM CORP (JP) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006124546-A2 | HEAT-SENSITIVE RECORD MATERIAL | APPLETON PAPERS INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060264326-A1 | Heat-sensitive record material | APPLETON PAPERS INC. (US) | 2006-11-23 | — | — | US | disclosed |
| US-6995784-B2 | Secure point of sale imageable substrate | APPLETON PAPERS INC. (US) | 2006-02-07 | — | — | US | disclosed |
| EP-1573685-A3 | SECURE POINT OF SALE IMAGEABLE SUBSTRATE | Appleton Papers Inc. (US) | 2005-09-22 | — | — | EP | disclosed |
| EP-1573685-A2 | SECURE POINT OF SALE IMAGEABLE SUBSTRATE | Appleton Papers Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| US-6773104-B2 | ULTRAVIOLET BLOCKING MATERIAL CHARACTERIZED IN THAT, A TRANSMITTANCE FOR THE LIGHT WITHIN A WAVELENGTH RANGE OF 300-380 NM IS 10% OR LESS AND A TRANSMITTANCE FOR THE LIGHT WITHIN A WAVELENGTH RANGE OF 420-800 NM IS 90% OR MORE | OPTICAL TECHNOLOGIES CORP. | 2004-08-10 | — | — | US | disclosed |
| US-20040104992-A1 | Secure point of sale imageable substrate | APPLETON PAPERS INC. (US) | 2004-06-03 | — | — | US | disclosed |
| WO-2004044852-A2 | SECURE POINT OF SALE IMAGEABLE SUBSTRATE | APPLETON, PAPERS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20030194385-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING SOLUBILIZED HYDROQUINONE, SALICYLIC ACID AND HYDROCORTISONE FOR THE TREATMENT OF MELASMA AND RELATED DERMATOLOGICAL PROBLEMS | LILA GRUBER RESEARCH FOUNDATION (US) | 2003-10-16 | — | — | US | disclosed |
| EP-1352195-A1 | ULTRAVIOLET FILTER COATING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-20030170467-A1 | Ultraviolet filter coating | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-09-11 | — | — | US | disclosed |
| WO-2002008664-A9 | ULTRAVIOLET FILTER COATING | CORNELIUS LESTER E (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2002008664-A1 | ULTRAVIOLET FILTER COATING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-31 | — | — | WO | disclosed |
| CN-1137556-A | Modified gas desulfurization method | WEI XIONGHUI (CN) | 1996-12-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194385-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING SOLUBILIZED HYDROQUINONE, SALICYLIC ACID AND HYDROCORTISONE FOR THE TREATMENT OF MELASMA AND RELATED DERMATOLOGICAL PROBLEMS | MC1R, MC2R, HMGCR | ALDH1A1 903/4885HPGD 182/4885KDM4E 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.