Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 5/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200886 | 0.91 | TPSAB1 (0.39) | NPY4RNPY1RTPSAB1TDP1MEN1 | |
| SCHEMBL6901610 | 0.90 | CNR1 (0.43) | TDP1MEN1KMT2ACASR | |
| SCHEMBL1389117 | 0.89 | CNR1 (0.41) | F10PRSS1NPY4RNPY1RTDP1 | |
| SCHEMBL1388355 | 0.88 | TDP1 (0.37) | NPY4RNPY1RTPSAB1TDP1MEN1 | |
| SCHEMBL4650866 | 0.85 | NPY1R (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9200988 | 0.85 | CYP2C9 (0.38) | F10NPY1RTDP1MEN1KMT2A | |
| SCHEMBL8121296 | 0.83 | F2 (0.38) | F2F10PRSS1NR3C1TPSAB1 | |
| SCHEMBL9276101 | 0.82 | CNR1 (0.39) | NPY1RTPSAB1 | |
| SCHEMBL9202531 | 0.81 | MEN1 (0.38) | F10PRSS1NPY4RNPY1RMEN1 | |
| SCHEMBL8120634 | 0.80 | PRSS1 (0.37) | F2F10PRSS1NR3C1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |