Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650906 | 0.88 | NPC1 (0.31) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1452556 | 0.75 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1452812 | 0.75 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL4652193 | 0.74 | ALDH1A1 (0.38) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1452779 | 0.71 | PGR (0.38) | NPC1ALDH1A1RAB9A | |
| SCHEMBL1451517 | 0.71 | PGR (0.38) | NPC1ALDH1A1RAB9A | |
| SCHEMBL4652200 | 0.70 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL1452217 | 0.69 | ALDH1A1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1454099 | 0.69 | ALDH1A1 (0.37) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1453777 | 0.67 | PGR (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |