Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652201 | 0.81 | SLC6A2 (0.46) | MAPK1PGRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4652193 | 0.80 | ALDH1A1 (0.38) | ALDH1A1PGRMAPTSLC6A2SLC6A4 | |
| SCHEMBL1452678 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPK1PGRMAOAMAOB | |
| SCHEMBL1451517 | 0.75 | PGR (0.38) | ALDH1A1MAPK1PGRMAOAMAOB | |
| SCHEMBL1452779 | 0.75 | PGR (0.38) | ALDH1A1MAPK1PGRMAOAMAOB | |
| SCHEMBL1453777 | 0.74 | PGR (0.37) | ALDH1A1MAPK1PGRMAOAMAOB | |
| SCHEMBL4650906 | 0.73 | NPC1 (0.31) | ALDH1A1 | |
| SCHEMBL15617728 | 0.70 | MAOA (0.38) | MAOAMAOBTP53ELANESLC6A2 | |
| SCHEMBL22744881 | 0.69 | SLC6A2 (0.44) | MAPK1PGRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4652079 | 0.69 | KDM1A (0.33) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |