Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651707 | 1.00 | TSHR (0.48) | TSHRTP53PLA2G4BLMNAALDH1A1 | |
| SCHEMBL4651612 | 1.00 | TSHR (0.48) | TSHRTP53PLA2G4BLMNAALDH1A1 | |
| SCHEMBL4651631 | 0.87 | LMNA (0.46) | TSHRTP53LMNAALDH1A1MEN1 | |
| SCHEMBL10430095 | 0.84 | FAAH (0.49) | TSHRTP53LMNAALDH1A1MEN1 | |
| SCHEMBL4651959 | 0.83 | PLK1 (0.61) | LMNAALDH1A1PTPN11MEN1KMT2A | |
| SCHEMBL4650949 | 0.83 | PLK1 (0.61) | LMNAALDH1A1PTPN11MEN1KMT2A | |
| SCHEMBL4651952 | 0.83 | PLK1 (0.61) | LMNAALDH1A1PTPN11MEN1KMT2A | |
| SCHEMBL4652909 | 0.80 | ALDH1A1 (0.51) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4651616 | 0.79 | CXCR2 (0.51) | TSHRTP53PLA2G4BLMNAALDH1A1 | |
| SCHEMBL4651710 | 0.79 | CXCR2 (0.51) | TSHRTP53PLA2G4BLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |