1,6-Hexanediol

1,6-Hexanediol

SCHEMBL4650951

CC(C)(C)COC(=O)CCCCC(=O)O.OCCCCCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
CAMK2A Q9UQM7 1/20 0.43
PAM P19021 2/20 0.43
TSHR P16473 6/20 0.41
LMNA P02545 1/20 0.41
NFKB1 P19838 1/20 0.41
PMP22 Q01453 1/20 0.41
ALDH1A1 P00352 3/20 0.40
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
HDAC11 Q96DB2 5/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
PTPN1 P18031 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL2487660 0.98 GPR84 (0.53) GPR84FFAR1FFAR4CAMK2APAM
1,4-Butanediol SCHEMBL8898729 0.97 GPR84 (0.50) GPR84FFAR1FFAR4CAMK2APAM
Ethylene Glycol SCHEMBL27871894 0.95 GPR84 (0.47) GPR84FFAR1FFAR4PAMTSHR
Ethylene Glycol SCHEMBL6238771 0.93 TSHR (0.44) GPR84FFAR1FFAR4CAMK2APAM
SCHEMBL13597953 0.93 DGKA (0.44) GPR84FFAR1FFAR4PAMTSHR
SCHEMBL7680019 0.93 PAM (0.48) GPR84FFAR1FFAR4PAMTSHR
SCHEMBL7047237 0.93 PAM (0.48) GPR84FFAR1FFAR4PAMTSHR
SCHEMBL27804161 0.93 PAM (0.48) GPR84FFAR1FFAR4PAMTSHR
SCHEMBL28869403 0.91 DGKA (0.41) GPR84FFAR1FFAR4PAMTSHR
SCHEMBL852014 0.91 TSHR (0.48) GPR84FFAR1FFAR4PAMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971427-A1 VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS Henkel Corporation (US) 2008-09-24 EP claimed
WO-2007078851-A1 VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS HENKEL CORPORATION (US) 2007-07-12 WO claimed