SCHEMBL465154

SCHEMBL465154

O=C(O)c1ccc2cc(OCCOc3ccc4c(CCO)c(C(=O)O)ccc4c3)ccc2c1CCO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.42
SLC16A3 O15427 1/20 0.40
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PTPN7 P35236 1/20 0.38
MEN1 O00255 1/20 0.38
CASP3 P42574 1/20 0.38
KMT2A Q03164 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
PRKAB2 O43741 1/20 0.38
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38
PRKAA1 Q13131 1/20 0.38
PRKAG3 Q9UGI9 1/20 0.38
PRKAG2 Q9UGJ0 1/20 0.38
PRKAB1 Q9Y478 1/20 0.38
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078780 0.80 PTPN1 (0.53) KDM4E
SCHEMBL18917572 0.74 WDR5 (0.58) KDM4EALDH1A1
SCHEMBL29712519 0.71 ALDH1A1 (0.58) MCL1ALDH1A1
SCHEMBL125463 0.71 CYP1A2 (0.48) KDM4EALDH1A1TDP1
SCHEMBL29664884 0.71 CYP1A2 (0.48) KDM4EALDH1A1TDP1
SCHEMBL14104475 0.71 ALDH1A1 (0.53) ALDH1A1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL9305167 0.70 MEN1 (0.56) KDM4EALDH1A1PTPN7MEN1CASP3
SCHEMBL10421503 0.69 PTPN11 (0.55)
SCHEMBL7819861 0.69 PTPN11 (0.55)
Ethylene Glycol SCHEMBL25436654 0.69 CYP1A2 (0.46) KDM4EALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116560-B1 POLYESTER, COMPOSITION THEREOF AND FILM THEREOF TEIJIN LTD (JP) 2012-01-11 EP disclosed
US-8017715-B2 Polyester, and composition and film comprising the same TEIJIN LIMITED (JP) 2011-09-13 US disclosed
US-7884173-B2 comprising 6,6'-(alkylenedioxy)di-2-naphthoic acid as the main dicarboxylic acid component; having excellent heat resistance, color, mechanical properties, dimensional stability and gas barrier properties TEIJIN LIMITED (JP) 2011-02-08 US disclosed
US-20100120967-A1 POLYESTER, AND COMPOSITION AND FILM COMPRISING THE SAME TEIJIN LIMITED (JP) 2010-05-13 US disclosed
US-20100016539-A1 AROMATIC POLYESTER AND MANUFACTURING PROCESS THEREOF TEIJIN LIMITED (JP) 2010-01-21 US disclosed
EP-2116560-A1 POLYESTER, COMPOSITION THEREOF AND FILM THEREOF Teijin Limited (JP) 2009-11-11 EP disclosed
EP-2045281-A1 AROMATIC POLYESTER AND METHOD FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2009-04-08 EP disclosed