Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975923 | 0.80 | ALDH1A1 (0.61) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL4651653 | 0.75 | MAPK1 (0.71) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL31347574 | 0.75 | MAPK1 (0.71) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL4650801 | 0.74 | CNR2 (0.50) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL4651631 | 0.73 | LMNA (0.46) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL9495325 | 0.71 | LMNA (1.00) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL1031488 | 0.71 | LMNA (0.71) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL20839925 | 0.71 | LMNA (0.65) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL3181802 | 0.70 | MAPK1 (0.59) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL9025214 | 0.70 | LMNA (0.69) | LMNAMAPK1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |