Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651631 | 0.80 | LMNA (0.46) | CNR2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL4650805 | 0.78 | LMNA (0.56) | CNR2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL28322841 | 0.77 | CNR2 (0.46) | CNR2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4651650 | 0.74 | LMNA (0.56) | MAPK1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL16976880 | 0.72 | CNR2 (0.41) | CNR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4651635 | 0.72 | LMNA (0.55) | CNR2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL13098077 | 0.71 | KMT2A (0.53) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| Hexadecane SCHEMBL28894271 | 0.70 | TSHR (0.68) | MAPK1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL4652862 | 0.69 | GPR35 (0.47) | — | |
| SCHEMBL17975923 | 0.69 | ALDH1A1 (0.61) | MAPK1LMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |