Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 13/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.35 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751511 | 0.84 | MASP2 (0.48) | NPY1RNPFFR1NPFFR2NPY5RMCHR1 | |
| SCHEMBL7750601 | 0.79 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL7746038 | 0.77 | NPY1R (0.46) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL7801972 | 0.77 | NPY1R (0.42) | NPY1RNPFFR1NPFFR2NPY5RMCHR1 | |
| SCHEMBL8111678 | 0.76 | ITGB3 (0.32) | — | |
| SCHEMBL4651991 | 0.76 | ITGB3 (0.32) | — | |
| SCHEMBL8119514 | 0.75 | HDAC1 (0.56) | NPY1RNPFFR1NPFFR2MCHR1PADI4 | |
| SCHEMBL4650854 | 0.75 | MCHR1 (0.50) | MCHR1PADI4PADI2 | |
| SCHEMBL7793040 | 0.74 | CHRM2 (0.40) | NPY1RNPFFR1NPFFR2NPY5RMCHR1 | |
| SCHEMBL8112599 | 0.73 | NPY1R (0.51) | NPY1RNPFFR1NPFFR2NPY5RMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |