Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801972 | 0.88 | NPY1R (0.42) | PADI4PADI2ITGB3ITGAVITGA2B | |
| SCHEMBL4650854 | 0.87 | MCHR1 (0.50) | PADI4PADI2FOLH1ITGB3ITGAV | |
| SCHEMBL7746038 | 0.82 | NPY1R (0.46) | NPY1RNPFFR1NPFFR2NPY5R | |
| SCHEMBL8119514 | 0.82 | HDAC1 (0.56) | PADI4PADI2NPY1RNPFFR1NPFFR2 | |
| SCHEMBL7750601 | 0.81 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5R | |
| SCHEMBL8121288 | 0.78 | SIRT5 (0.49) | CHRM2CHRM1CHRM3FOLH1ITGB3 | |
| SCHEMBL7750609 | 0.75 | ROCK1 (0.38) | ITGB3ITGAVITGA2BKDM4E | |
| SCHEMBL8112599 | 0.75 | NPY1R (0.51) | NPY1RNPFFR1NPFFR2NPY5RMCHR1 | |
| SCHEMBL4651985 | 0.74 | NPY1R (0.38) | PADI4PADI2NPY1RNPFFR1NPFFR2 | |
| SCHEMBL7751511 | 0.73 | MASP2 (0.48) | PADI4PADI2NPY1RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |