Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652203 | 0.86 | LMNA (0.31) | — | |
| SCHEMBL4653367 | 0.81 | KCNH2 (0.32) | — | |
| SCHEMBL4652002 | 0.80 | PPARG (0.33) | — | |
| SCHEMBL1452572 | 0.79 | CRHBP (0.39) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL4651165 | 0.78 | — | — | |
| SCHEMBL1452311 | 0.78 | CRHBP (0.40) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL1452192 | 0.78 | CRHBP (0.40) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL1453331 | 0.77 | CRHBP (0.39) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL4652286 | 0.75 | — | — | |
| SCHEMBL4653310 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |