Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 12/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654556 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BACHESLC6A5NOD1 | |
| SCHEMBL4653394 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BACHESLC6A5NOD1 | |
| SCHEMBL4652510 | 0.88 | EPHX2 (0.48) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL127678 | 0.88 | SLC6A5 (0.49) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL9885941 | 0.88 | SLC6A5 (0.49) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL7167413 | 0.88 | SLC6A5 (0.49) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL16054385 | 0.88 | SLC6A5 (0.49) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL4653498 | 0.88 | EPHX2 (0.48) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL9665935 | 0.85 | SLC6A5 (0.54) | ITGB3ITGA2BSLC6A5NOD1 | |
| SCHEMBL13279668 | 0.85 | SLC6A5 (0.54) | ITGB3ITGA2BSLC6A5NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562789-B2 | Free radical scavenger in cosmetics, drugs | L'OREAL S.A. (FR) | 2003-05-13 | — | — | US | claimed |
| EP-0972511-B1 | Association of a retinoid with a histidine derivative | OREAL (FR) | 2003-04-09 | — | — | EP | claimed |
| US-20020165165-A9 | New histidine derivatives, preparation process, and their use as free antiradical agents | L'OREAL S.A. | 2002-11-07 | — | — | US | claimed |
| EP-0946516-B1 | NEW HISTIDINE DERIVATIVES, PREPARATION PROCESS, AND THEIR USE AS FREE ANTIRADICAL AGENTS | OREAL (FR) | 2002-04-10 | — | — | EP | claimed |
| US-6358514-B1 | FOR SKIN AND HAIRCARE | L'OREAL (FR) | 2002-03-19 | — | — | US | claimed |
| US-20010031732-A1 | New histidine derivatives, preparation process, and their use as free antiradical agents | L'OREAL S.A. | 2001-10-18 | — | — | US | claimed |
| US-6255344-B1 | COSMETICS; DRUGS; OXIDATION RESISTANCE | L'OREAL S.A. (FR) | 2001-07-03 | — | — | US | claimed |
| EP-0972511-A1 | Association of a retinoid with a histidine derivative | L'OREAL (FR) | 2000-01-19 | — | — | EP | claimed |
| EP-0946516-A1 | NEW HISTIDINE DERIVATIVES, PREPARATION PROCESS, AND THEIR USE AS FREE ANTIRADICAL AGENTS | L'OREAL (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998024770-A1 | NEW HISTIDINE DERIVATIVES, PREPARATION PROCESS, AND THEIR USE AS FREE ANTIRADICAL AGENTS | L'OREAL (FR) | 1998-06-11 | — | — | WO | claimed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20010031732-A1 | New histidine derivatives, preparation process, and their use as free antiradical agents | L'OREAL S.A. | 2001-10-18 | — | — | US | disclosed |
| US-6255344-B1 | COSMETICS; DRUGS; OXIDATION RESISTANCE | L'OREAL S.A. (FR) | 2001-07-03 | — | — | US | disclosed |
| EP-0972511-A1 | Association of a retinoid with a histidine derivative | L'OREAL (FR) | 2000-01-19 | — | — | EP | disclosed |
| EP-0946516-A1 | NEW HISTIDINE DERIVATIVES, PREPARATION PROCESS, AND THEIR USE AS FREE ANTIRADICAL AGENTS | L'OREAL (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024770-A1 | NEW HISTIDINE DERIVATIVES, PREPARATION PROCESS, AND THEIR USE AS FREE ANTIRADICAL AGENTS | L'OREAL (FR) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031732-A1 | New histidine derivatives, preparation process, and their use as free antiradical agents | HRH1, HRH4, H1-0 | ITGB3 3918/4885ITGA2B 4077/4885ACHE 2811/4885 |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | ITGB3 4676/4885ITGA2B 4586/4885ACHE 4326/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | ITGB3 3766/4885ITGA2B 3118/4885ACHE 1514/4885 |
| US-20020165165-A9 | New histidine derivatives, preparation process, and their use as free antiradical agents | HRH1, HRH4, H1-0 | ITGB3 3918/4885ITGA2B 4077/4885ACHE 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.