Diphenylamine

Diphenylamine

SCHEMBL4735870

C(=Cc1ccc(-c2ccc(C=Cc3ccccc3)cc2)cc1)c1ccccc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 3/20 0.52
ALOX12 P18054 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
MAPK1 P28482 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAOB P27338 3/20 0.48
MAOA P21397 2/20 0.48
NFE2L2 Q16236 1/20 0.48
CYP19A1 P11511 1/20 0.48
PDE5A O76074 1/20 0.47
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
AR P10275 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971893 0.93 HSD17B10 (0.50) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL7782610 0.93 HSD17B10 (0.63) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL465276 0.91 ALDH1A1 (0.65) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL465277 0.91 ALDH1A1 (0.65) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
(Z)-1,2-Diphenylethene SCHEMBL1877462 0.91 HSD17B10 (0.67) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL293235 0.88 ALDH1A1 (0.60) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL10042620 0.88 ALDH1A1 (0.60) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL3372676 0.88 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL3374038 0.88 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL18898939 0.86 HPGD (0.67) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008067673-A1 ORGANIC ELECTROLUMINESCENT MATERIALS, APPARATUS, SYSTEMS, AND METHODS ORGANIC VISIONS INC. (CA) 2008-06-12 WO claimed
WO-2008067673-A1 ORGANIC ELECTROLUMINESCENT MATERIALS, APPARATUS, SYSTEMS, AND METHODS ORGANIC VISIONS INC. (CA) 2008-06-12 WO disclosed