Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653106 | 0.85 | TP53 (0.44) | NPY1RTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9202898 | 0.84 | NPY1R (0.40) | NPY1RTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8119334 | 0.84 | NPY1R (0.47) | NPY1RNPY4RNPY5RNPY2RNPFFR1 | |
| SCHEMBL4653101 | 0.80 | NPY1R (0.54) | NPY1RNPY4RNPY5RNPY2RNPFFR1 | |
| SCHEMBL8120771 | 0.78 | NPY1R (0.44) | NPY1RNPY4RNPY5RNPY2RNPFFR1 | |
| SCHEMBL8112566 | 0.78 | TP53 (0.40) | NPY1RTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9195765 | 0.77 | TP53 (0.40) | NPY1RTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8122083 | 0.77 | NPY1R (0.40) | NPY1RNPY4RNPY5RNPY2RNPFFR1 | |
| SCHEMBL8122078 | 0.76 | CASR (0.44) | NPY1RTDP1 | |
| SCHEMBL8120923 | 0.75 | NPY1R (0.39) | NPY1RNPY4RNPY5RNPY2RNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |