Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142291 | 0.78 | CES2 (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL10464263 | 0.77 | CA12 (0.56) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3317813 | 0.76 | ALDH1A1 (0.44) | SIRT2HSD17B1HSD17B2ABL1ALDH1A1 | |
| SCHEMBL3317810 | 0.76 | ALDH1A1 (0.44) | SIRT2HSD17B1HSD17B2ABL1ALDH1A1 | |
| SCHEMBL8654881 | 0.72 | CA1 (0.52) | ALDH1A1MAPTCYP19A1 | |
| SCHEMBL14339176 | 0.70 | HSD17B1 (0.37) | SIRT2HSD17B1HSD17B2ABL1ALDH1A1 | |
| SCHEMBL4626690 | 0.68 | ITGB1 (0.55) | — | |
| SCHEMBL3315261 | 0.68 | ESR1 (0.63) | HSD17B1HSD17B2ABL1MEN1KMT2A | |
| SCHEMBL10465657 | 0.68 | ALDH1A1 (0.52) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL2040154 | 0.68 | CA1 (0.55) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | claimed |