Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652644 | 0.93 | ALDH1A1 (0.62) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL4653865 | 0.78 | HTT (0.62) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL4653945 | 0.77 | GAA (0.45) | ALDH1A1LMNARXRARXRBRXRG | |
| SCHEMBL22226781 | 0.75 | LMNA (0.82) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL4653850 | 0.75 | GAA (0.56) | ALDH1A1LMNAPOLBMAPTPKM | |
| SCHEMBL3006703 | 0.74 | HTT (0.79) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL8786021 | 0.73 | MAOB (0.61) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL13323 | 0.70 | ALDH1A1 (0.60) | ALDH1A1LMNAMAOBMAOAHTT | |
| SCHEMBL211460 | 0.70 | TSHR (0.44) | ALDH1A1LMNAHTTHPGDRXRA | |
| SCHEMBL4652613 | 0.70 | HTT (0.76) | ALDH1A1LMNAMAOBMAOAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844029-B1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | SERVIER LAB (FR) | 2008-11-12 | — | — | EP | disclosed |
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | LES LABORATOIRES SERVIER (FR) | 2008-05-15 | — | — | US | disclosed |
| EP-1844029-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | Les Laboratoires Servier (FR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079720-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | CBR1, CYP3A7, CYP2C9 | ALDH1A1 521/4885LMNA 3130/4885MAOB 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.