Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4463624 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL11672231 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL11672430 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL11619467 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL11672035 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL11671892 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL39345 | 0.96 | TSHR (0.50) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL3791346 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL3199493 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL4238292 | 0.93 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110231754-B | Heterocyclic multifunctional photoinduced acid generator, preparation method thereof and prepared chemical amplification type photoresist | 苏州瑞红电子化学品有限公司 | 2023-05-02 | — | — | CN | claimed |
| EP-3844239-A1 | USE OF SULFONIUM SALTS AS CORROSION INHIBITORS | ChampionX USA Inc. (US) | 2021-07-07 | — | — | EP | claimed |
| US-10900128-B2 | Use of sulfonium salts as corrosion inhibitors | CHAMPIONX USA INC. (US) | 2021-01-26 | — | — | US | claimed |
| CN-111302979-A | Single-component molecular glass and preparation method and application thereof | 苏州瑞红电子化学品有限公司 | 2020-06-19 | — | — | CN | claimed |
| EP-1347012-B2 | Curable Fluoroelastomers | SOLVAY SPECIALTY POLYMERS IT (IT) | 2020-04-29 | — | — | EP | claimed |
| WO-2020047193-A1 | USE OF SULFONIUM SALTS AS CORROSION INHIBITORS | ECOLAB USA INC. (US) | 2020-03-05 | — | — | WO | claimed |
| US-20200071840-A1 | USE OF SULFONIUM SALTS AS CORROSION INHIBITORS | HARBISON-FISCHER, INC. | 2020-03-05 | — | — | US | claimed |
| US-20180245004-A1 | USE OF SULFONIUM SALTS AS HYDROGEN SULFIDE INHIBITORS | CHAMPIONX LLC | 2018-08-30 | — | — | US | claimed |
| US-7767764-B2 | Fluoroelastomers | SOLVAY SOLEXIS S.P.A. (IT) | 2010-08-03 | — | — | US | claimed |
| US-7705083-B2 | blends comprising vinylidene fluoride copolymer can be curable by ionic route, accelerator, curing agent; low compression set values; improved sealing properties; improved compression set on O-ring | SOLVAY SOLEXIS S.P.A. (IT) | 2010-04-27 | — | — | US | claimed |
| EP-1347012-B1 | Curable Fluoroelastomers | SOLVAY SOLEXIS SPA (IT) | 2006-12-20 | — | — | EP | claimed |
| US-20050245691-A1 | Curable fluoroelastomers | SOLVAY SOLEXIS S.P.A. | 2005-11-03 | — | — | US | claimed |
| EP-1591479-A1 | Curable Fluorelastomers | Solvay Solexis S.p.A. (IT) | 2005-11-02 | — | — | EP | claimed |
| US-6664338-B2 | Polymer curable by ionic route comprising fluoroelastomer based on vinylidene fluoride having amount of polar end group lower than 3% by moles, accelerant, curing agent, inorganic acid acceptors, basic compounds, reinforcing fillers | AUSIMONT S.P.A. (IT) | 2003-12-16 | — | — | US | claimed |
| US-20030187144-A1 | Curable fluoroelastomers | AUSIMONT S.P.A. | 2003-10-02 | — | — | US | claimed |
| EP-1347012-A2 | Curable Fluoroelastomers | Solvay Solexis S.p.A. (IT) | 2003-09-24 | — | — | EP | claimed |
| EP-0833857-B1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5756588-A | CURABLE COMPOSITION COMPRISING FLUOROPOLYMER, AROMATIC POLYHYDROXY CROSSLINKING AGENT, ORGANO-ONIUM COMPOUND, MONOHYDROXYFUNCTIONAL PHENOL CAPABLE OF DELAYING POST-COMPOUNDING INITIATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180245004-A1 | USE OF SULFONIUM SALTS AS HYDROGEN SULFIDE INHIBITORS | STS, TST, ARSA | TSHR 1433/4885THRB 1526/4885LMNA 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.