SCHEMBL465452

SCHEMBL465452

CC(C)NC(CCO)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
FOLH1 Q04609 5/20 0.38
NAALAD2 Q9Y3Q0 4/20 0.38
TGFBR1 P36897 3/20 0.38
ACE P12821 1/20 0.35
RIMKLA Q8IXN7 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
PTGS2 P35354 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MME P08473 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16750035 1.00 ALDH1A1 (0.39) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL25761614 1.00 ALDH1A1 (0.39) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL2163632 0.83 GABRP (0.40) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL5131687 0.82 CHRM1 (0.46) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL16658841 0.82 ALDH1A1 (0.44) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL16750050 0.82 CHRM1 (0.46) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL5131686 0.82 CHRM1 (0.46) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL9911356 0.81 TGFBR1 (0.50) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL16750049 0.81 TGFBR1 (0.50) ALDH1A1MEN1LMNAKMT2AFOLH1
SCHEMBL16750052 0.81 TGFBR1 (0.50) ALDH1A1MEN1LMNAKMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118356514-A MRNA-LNP delivery system, preparation method and application thereof 上海赛丽莱生物科技有限公司 2024-07-19 CN claimed
CN-114099699-B Nanometer delivery system and preparation method and application thereof 华南理工大学 2024-03-19 CN claimed
CN-115414476-A Modified magnesium oxide, magnesium-containing nanoparticle aqueous solution, preparation method thereof and application thereof in preparation of adjuvant 珠海暨创硒源纳米科技有限公司 2022-12-02 CN claimed
CN-114099699-A Nano delivery system and preparation method and application thereof 华南理工大学 2022-03-01 CN claimed
CN-118356514-A MRNA-LNP delivery system, preparation method and application thereof 上海赛丽莱生物科技有限公司 2024-07-19 CN disclosed
CN-118324715-A Compounds, compositions, and methods of use thereof 艾勒维生技公司 2024-07-12 CN disclosed
CN-117750962-A Compounds, compositions, and methods of use thereof 艾勒维生技公司 2024-03-22 CN disclosed
CN-114099699-B Nanometer delivery system and preparation method and application thereof 华南理工大学 2024-03-19 CN disclosed
CN-113698309-B Method for extracting and separating betaine fat from bolete 中南民族大学 2024-02-06 CN disclosed
CN-116916943-A Encapsulated RNA polynucleotides and methods of use 昂克诺斯公司 2023-10-20 CN disclosed
CN-115414476-B Modified magnesium oxide, magnesium-containing nanoparticle aqueous solution, preparation method thereof and application thereof in preparing adjuvant 珠海暨创硒源纳米科技有限公司 2023-07-14 CN disclosed
EP-4198017-A1 BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2023-06-21 EP disclosed
WO-2008009071-A2 COMBINATION THERAPY USING BETAINE AND ENDOTHELIN ANTAGONISTS MESSADEK JALLAL (BE) 2008-01-24 WO disclosed
EP-1615632-B1 FLOATING ORAL FORMULATIONS FOR CONTROLLED RELEASE OF BETAINE MESSADEK JALLAL (BE) 2006-12-06 EP disclosed
WO-2006113978-A2 INSULINS COMBINATIONS MESSADEK JALLAL (BE) 2006-11-02 WO disclosed
WO-2006086856-A1 COMBINATION THERAPEUTIC COMPOSITIONS AND METHOD OF USE MESSADEK, JALLAL (BE) 2006-08-24 WO disclosed
EP-1615632-A1 FLOATING ORAL FORMULATIONS FOR CONTROLLED RELEASE OF BETAINE Messadek, Jallal (BE) 2006-01-18 EP disclosed
EP-1569692-A2 BETAINE AND SALICYLIC ACID COMPOSITIONS Messadek, Jallal (BE) 2005-09-07 EP disclosed
WO-2004091601-A1 FLOATING ORAL FORMULATIONS FOR CONTROLLED RELEASE OF BETAINE MESSADEK JALLAL (BE) 2004-10-28 WO disclosed
WO-2004049095-A2 BETAINE AND SALICYLIC ACID COMPOSITIONS MESSADEK JALLAL (BE) 2004-06-10 WO disclosed