Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652287 | 0.83 | CYP3A4 (0.41) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL4653378 | 0.82 | MEN1 (0.46) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL4653345 | 0.78 | MAPT (0.44) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL4654495 | 0.78 | MEN1 (0.44) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL4653651 | 0.75 | LMNA (0.44) | LMNAMAPTHTTNPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL10683206 | 0.73 | MEN1 (0.44) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10362320 | 0.73 | CYP3A4 (0.42) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10679804 | 0.72 | CYP3A4 (0.42) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10685178 | 0.70 | CYP3A4 (0.40) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL14641553 | 0.70 | CYP3A4 (0.46) | CYP3A4CYP2D6MAPK1MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987009-A1 | CYCLOUREA COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2008-11-05 | — | — | EP | claimed |
| WO-2007085357-A1 | CYCLOUREA COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-02 | — | — | WO | claimed |