Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MLNR | O43193 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653651 | 0.87 | LMNA (0.44) | MAPTCYP19A1NPSR1LMNAHTT | |
| SCHEMBL4654585 | 0.78 | CYP3A4 (0.46) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4652287 | 0.75 | CYP3A4 (0.41) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4654495 | 0.75 | MEN1 (0.44) | MAPTNPSR1TSHRUSP2MEN1 | |
| SCHEMBL4653378 | 0.74 | MEN1 (0.46) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4285624 | 0.71 | RAB9A (0.44) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4285362 | 0.67 | CYP19A1 (0.42) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4652605 | 0.67 | CYP19A1 (0.40) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL4652536 | 0.65 | PARG (0.43) | MAPTCYP19A1NPSR1TSHRUSP2 | |
| SCHEMBL10362320 | 0.64 | CYP3A4 (0.42) | MAPTCYP19A1NPSR1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987009-A1 | CYCLOUREA COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007085357-A1 | CYCLOUREA COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-02 | — | — | WO | disclosed |