SCHEMBL4655017

SCHEMBL4655017

CCCC(Oc1cc(O)cc(F)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.54
PPARA Q07869 11/20 0.54
PTGES O14684 1/20 0.42
ALOX5 P09917 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
ALDH2 P05091 2/20 0.38
HCAR1 Q9BXC0 1/20 0.38
CTRC Q99895 1/20 0.36
FOLH1 Q04609 1/20 0.35
CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4798989 0.79 PPARG (0.64) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL28745487 0.78 PPARG (0.63) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL2106689 0.78 PPARG (0.63) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL8527020 0.76 SMN1; SMN2 (0.60) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL11144367 0.75 PPARG (0.55) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL5508320 0.73 PPARG (0.73) PPARGPPARAPTGESALOX5
SCHEMBL8935946 0.73 PPARG (0.73) PPARGPPARAPTGESALOX5
SCHEMBL5317260 0.71 PTGS2 (0.56) PPARGPPARAPTGESALOX5CTRC
SCHEMBL30233468 0.71 PPARG (0.50) PPARGPPARAPTGESALOX5SMN1; SMN2
SCHEMBL14293619 0.71 PPARG (0.54) PPARGPPARAPTGESALOX5SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
CN-1260265-C Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2006-06-21 CN disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 CN disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed